Mesothelioma-mimicking multiple myeloma with dumbbell-type progression.

نویسندگان

  • Teruhiko Sekiguchi
  • Yoichiro Nishida
  • Akira Inaba
  • Shigeo Toyota
چکیده

An 80-year-old man, exposed to asbestos in a dockyard, suffered from progressive paraplegia for two months. His plantar reflexes were bilaterally abnormal and Romberg’s sign was positive. Spine MRI revealed that the thoracic cord was compressed by the mass in the dorsal epidural space (Picture 1). Chest CT was suggestive of mesothelioma with dumbbell-shaped progression spreading from the right pleura over the thoracic vertebral body through the right intervertebral foramen (Picture 2A, B). However, IgG-lambda type monoclonal gammopathy and massive infiltration of welldifferentiated plasmacytes shown on a blood examination and a right pleura biopsy, respectively, confirmed the diagnosis of multiple myeloma (Picture 3). Plasmacytoma, including multiple myeloma, infrequently appears as an epidural spinal tumor, pleural tumor or dumbbell (dumb-bell) tumor penetrating the intervertebral

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Characteristics and outcomes of patients with multiple myeloma : Data from a developing country

Background: Multiple myeloma (MM) is a plasma cell disorder characterized by presence of monoclonal protein in serum or urine or both, increased bone marrow plasma cells, osteolytic lesion, hypercalcemia, and anemia. Several combination regimens are commonly recommended for treatment of multiple myeloma. The present study aimed at determining the characteristics and outcomes of patients with mu...

متن کامل

CD200: a putative therapeutic target in cancer.

CD200 was recently described as a new prognosis factor in multiple myeloma and acute myeloid leukemia. CD200 is a membrane glycoprotein that imparts an immunoregulatory signal through CD200R, leading to the suppression of T-cell-mediated immune responses. We investigated the expression of CD200 in cancer using publicly available gene expression data. CD200 gene expression in normal or malignant...

متن کامل

Role of Suppressed Immunoglobulins in Outcome of Patients With Multiple Myeloma

Introduction: Multiple myeloma (MM) is typically presented with abundant monoclonal secretion of one type of immunoglobulin. The other classes of immunoglobulins, which are uninvolved and not secreted by malignant plasma cells, could be decreased. A number of previous studies reported the effect of suppression of uninvolved immunoglobulins on the outcome of patients with myeloma. However, its e...

متن کامل

Role of Suppressed Immunoglobulins in Outcome of Patients With Multiple Myeloma

Introduction: Multiple myeloma (MM) is typically presented with abundant monoclonal secretion of one type of immunoglobulin. The other classes of immunoglobulins, which are uninvolved and not secreted by malignant plasma cells, could be decreased. A number of previous studies reported the effect of suppression of uninvolved immunoglobulins on the outcome of patients with myeloma. However, its e...

متن کامل

An Unusual Presentation of Plasma Cell Leukemia with Undiagnosed Multiple Myeloma

A 54 year old man with history of cardiomyopathy and chronic fibrillation first presented with bloody diarrhea. Then during the assessment of his abnormal lab. data revealed cast nephropathy in renal biopsy, gamma peak in protein electrophoresis and fine lytic lesions in skull graphy. His bone marrow asp...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Internal medicine

دوره 52 11  شماره 

صفحات  -

تاریخ انتشار 2013